Leidse hoogleraren vanaf 1575

Robert Verpoorte

Geboren
1946-05-17 te Eindhoven, Nederland
Geslacht
Man

Promotie (1976)

Type examen
Promotie
Datum
1976
Plaats
Leiden
Proefschrift
Pharmacognostical studies of some african Strychnos species

Gewoon Hoogleraar (1987)

Benoeming
Gewoon Hoogleraar
Faculteit
Wiskunde en Natuurwetenschappen
Vakgebied
Farmacie
Leeropdracht
Farmacognosie, in het bijzonder de plantencelbiotechnologie
Datum benoeming
1987-05-17
Datum ambtsaanvaarding
1987-12-01
Datum oratie
1989-03-10
Titel oratie
Secundaire plantenstoffen, primair belang

Publicaties

Wetenschappelijk
  • Akhtar M.T., Mushtaq M.Y., Verpoorte R., Richardson M.K. & Choi Y.H. (2016), Zebrafish as a Model for Systems Medicine R&D: Rethinking the Metabolic Effects of Carrier Solvents and Culture Buffers Determined by (1)H NMR Metabolomics., Omics : a journal of integrative biology 20(1): 42-52.
  • Ayouni K., Berboucha M., Kim H.K., Atmani D., Verpoorte R. & Choi Y.H. (2016), Metabolomic tool to identify antioxidant compounds of Fraxinus angustifolia leaf and stem bark extracts., Industrial Crops and Products 88: 65-77.
  • Schilthuizen M., Santos Pimenta L.P., Lammers Y., Steenbergen P.J., Flohil M., Beveridge N.G., Duijn P.T. van, Meulblok M M., Sosef N., Ven R. van de, Werring R., Beentjes K K., Meijer K., Vos R.A., Vrieling K., Gravendeel B., Choi Y.H., Verpoorte R., Smit C. & Beukeboom L.W. (2016), Incorporation of an invasive plant into a native insect herbivore food web, PeerJ 4: e1954.
  • Coqueiro A., Choi Y.H., Verpoorte R., Gupta K.B.S.S., Mieri M. de, Hamburger M., Young M.C.M., Stapleton P. , Gibbons S. & Bolzani V.D.S. (2016), Anti-staphylococcal prenylated acylphloroglucinol and xanthones from Kielmeyera variabilis (Clusiaceae), Journal of Natural Products 79: 470-476.
  • Dai Y., Rozema E., Verpoorte R. & Choi Y. H. (2016), Application of natural deep eutectic solvents to the extraction of anthocyanins from Catharanthus roseus with high extractability and stability replacing conventional organic solvent., JOURNAL OF CHROMATOGRAPHY A 1434: 50-56.
  • Rozema E., van Dam A.D., Sips H.C.M., Verpoorte R., Meijer O.C., Kooijman S. & Choi Y.H. (2015), Extending pharmacological dose-response curves for salsalate with natural deep eutectic solvents, RSC ADVANCES 5(75): 61398-61401.
  • Dai Y., Witkamp G.J., Verpoorte R. & Choi Y.H. (2015), Tailoring properties of natural deep eutectic solvents with water to facilitate their applications, FOOD CHEMISTRY 187: 14-19.
  • Ali K., Verpoorte R., Wilson E.G., Choi Y.H. & (2015), Chemical Characterization of Marine Organisms Using e Metabolomic Approach In Marine Biotechnology. In: Baker B.J. (red.) From beach to Bedside.. Boca Raton FL USA: CRC press. 23-42.
  • Saiman M.Z., Mustafa N.R., Choi Y.H., Verpoorte R. & Schulte A.E. (2015), Metabolic alterations and distribution of five-carbon precursors in jasmonic acid-elicited Catharanthus roseus cell suspension cultures, PLANT CELL TISSUE AND ORGAN CULTURE 122(2): 351-362.
  • Mohd Zuwairi Bin Saiman M., Mustafa N.R., Pomahacova B., Verberne M., Verpoorte R., Choi Y.H. & Schulte A.E. (2015), Analysis of metabolites in the terpenoid pathway of Catharanthus roseus cell suspensions (Erratum to: vol 117, pg 225-239, 2014), Plant Cell Tissue and Organ Culture 122(1): 257-257.
  • Khoyratty S.U.S.S., Dupont J., Lacoste S., Palama T.L., Choi Y.H., Kim H.K., Payet B., Grisoni M., Fouillaud M., Verpoorte R. & Kodja H. (2015), Fungal endophytes of Vanilla planifolia across Reunion Island: isolation, distribution and biotransformation, BMC PLANT BIOLOGY 15(142).
  • Pan Q., Mustafa N.R., Tang K., Choi Y.H. & Verpoorte R. (2015), Monoterpenoid indole alkaloids biosynthesis and its regulation in Catharanthus roseus: a literature review from genes to metabolites, PHYTOCHEMISTRY REVIEWS 15(2): 221-250.
  • Zheng L., Wang M., Ibarra-Estrada E., Wu C., Wilson E.G., Verpoorte R., Klinkhamer P.G.L. & Choi Y.H. (2015), Investigation of Chemomarkers of Astragali Radix of Different Ages and Geographical Origin by NMR Profiling, MOLECULES 20(2): 3389-3405.
  • P.G.L. Klinkhamer, T.R. Nuringtyas, R. Verpoorte, M.M.Oers & K.A. Leiss (2014), Toxicity of Pyrrolizidine Alkaloids to Spodoptera exigua using insect cell lines and injection bioassays, Jounal of Chemical Ecology 40(6): 609 -616.
  • Miettinen K, Dong L, Navrot N, Schneider T, Burlat V, Pollier J, Woittiez L, van der Krol S, Lugan R, Ilc T, Verpoorte R, Oksman-caldentey KM, Martinoia E, Bouwmeester H, Goossens A, Memelink J & Werck-Reichhart D. (2014), The seco-iridoid pathway from Catharanthus roseus, Nature Communications 5: 3606.
  • Akhtar, M.T., Ali, S., Rashidi, H., Van der Kooy, F., Verpoorte, R., Richardson & M.K. (2013), Developmental effectsEffects of cannabinoidsCannabinoids on zebrafish larvaeZebrafish Larvae Zebrafish., European Neuropsychopharmacology 10: 283-293.
  • Goldhaber-Pasillas, G.D., Choi, Y.H., Verpoorte & R. (2013), New methods of analysis and investigation of terpenoid indole alkaloids., Elsevier 68: 233-272.
  • Toyang, N.J., Wabo, H.K., Ateh, E.N., Verpoorte & R. (2013), Cytotoxic sesquiterpene lactones from the leaves of Vernonia guinensis Benth., Journal of Ethnopharmacology 146: 552-556.
  • Yuliana, N.D., Korthout, H., Wijaya, C.H., Kim, H.K., Verpoorte & R. (2013), Plant-Derived Food Ingredients for Stimulation of Energy Expenditure., Critical Reviews in Food Science and Nutricion 54: 373-388.
  • Kim, H.K., Choi, Y.H., Verpoorte & R. (2013), Profiling the jasmonic acid responses by nuclear magnetic resonance-based metabolomics., Methods in Molecular Biology : 267-275.
  • Iqbal, M., Verpoorte, R., Korthout, H.A.A.J., Mustafa & N.R. (2013), Phytochemicals as a potential source for TNF-a inhibitors., Phytochemistry Reviews 12: 65-93.
  • Van der Sar, S., Kim, H.K., Meissner, A., Verpoorte, R., Choi & Y.H. (2013), Nuclear magnetic resonance spectroscopy for plant metabolite profiling.. In: The Handbook of Plant Metabolomics. Weinheim: Wiley-VCH.
  • Dai, Y., Van Spronsen, J., Witkamp, G.J., Verpoorte, R., Choi & Y.H. (2013), Natural Deep Eutectic Solvents as New Potential Media for Green Technology., Analytica Chimica Acta 766: 61-68.
  • Pimenta, L.P.S., Kim, H.K., Verpoorte, R., Choi & Y.H. (2013), NMR-based metabolomics: A probe to utilize biodiversity., Methods in Molecular Biology 1055: 117-127v.
  • Goldhaber-Pasillas, G.D., Choi, Y.H., Verpoorte & R. (2013), New Methods of Analysis and Investigation of Terpenoid Indole Alkaloids., Advances in Botanical Research 68: 233-272.
  • Lubbe, A., Ali, K., Verpoorte, R., Choi & Y.H. (2013), Metabolomics in practice: NMR-based metabolomics analysis.. In: Metabolomics in Practice, Successful Strategies to Generate and Analyze Metabolic Data. Weinheim: Wiley-VCH. 209-238.
  • Ali, K., Iqbal, M., Yuliana, N. D., Lee, Y.J., Park, S., Han, S., Lee, J.W., Lee, H.S., Verpoorte, R., Choi & Y.H. (2013), Identification of bioactive metabolites against adenosine A1 receptor using NMR-based Metabolomics., Metabolomics 9: 778-785.
  • Toyang, N.J., Ateh, E.N., Davis, H., Tane, P., Sondengam, L.B., Bryant, J., Verpoorte & R. (2013), In vivo antiprostate tumor potential of Vernonia guineensis Benth. (Asteraceae) tuber extract (VGDE) and the cytotoxicity of its major compound pentaisovaleryl sucrose., Journal of Ethnopharmacology 150: 724-728.
  • Dai, Y., van Spronsen, J. Witkamp, G.J., Verpoorte, R., Choi & Y.H. (2013), Ionic liquids and deep eutectic solvents in natural products research., Journal of Natural Products 76: 2162-2173.
  • Charoonratana, T., Pathompak, P., Keawpradub, H., Georgiev, M.I., Choi, Y.H., Verpoorte, R., Wungsintaweekul & J. (2013), Limitation of Mitragynine Biosynthesis in Mitragyna speciosa (Roxb.) Korth. through tryptamine availability., Zeitschrift fuer Naturforschung C : A Journal of Biosciences 68: 394-405.
  • Zárate, R., el Jaber-Vazdekis, N., Verpoorte & R. (2013), Metabolic Engineering of Plant Cellular Metabolism: Methodologies, Advances, and Future Directions.. In: Biotechnology for Medicinal Plants. Heidelberg: Springer-Verlag. 259-393.
  • Georgiev, M.I., Ivanovska, N., Alipieva, K., Dimitrova, P., Verpoorte & R. (2013), Harpagoside: from Kalahari Desert to pharmacy shelf., Phytochemistry 79: 8-15.
  • Charoonratana, T., Wungsintaweekul, J., Keawpradub, N., Verpoorte & R. (2013), Molecular cloning and expression of tryptophan decarboxylase from Mitragyna speciosa., Acta Physiologiae Plantarum 35: 2611-2621.
  • Ali, K., Iqbal, M., Fortes, A.M., Pais, M.S., Korthout, H.A.A.J., Verpoorte, R., Choi & Y.H. (2013), Red wines attenuate TNFα production in human histiocytic lymphoma cell line: An NMR spectroscopy and chemometrics based study., Food Chemistry 141: 3124-3130.
  • Yuliana, N.D., Jahangir, M., Verpoorte, R., Choi & Y.H. (2013), Metabolomics for the rapid dereplication of bioactive compounds from natural sources., Phytochemistry Reviews 12: 293-304.
  • Lopez-Gresa, M.P., Lison, P., Kim, H.K., Choi, Y.H., Verpoorte, R., Rodrigo, I., Conejero V., Bells & J.M. (2013), Metabolic fingerprinting of Tomato Mosaic Virus infected Solanum lycopersicum., Plant Physiology 169: 1586-1596.
  • Dai, L. Y., Witkamp, G. J., Verpoorte, R., Choi & Y. H. (2013), Natural deep eutectic solvents as a new extraction media for phenolic metabolites in Carthamus tinctorius., Analytical Chemistry 85: 6272-6278.
  • Goldhaber-Pasillas, G.D., Choi, Y.H., Verpoorte & R. (2013), New Methods of Analysis and Investigation of Terpenoid Indole Alkaloids., Advances in Botanical Research 68: 233-272.
  • Wahyuni, D.S., Van der Kooy, F., Klinkhamer, P.G.L., Verpoorte, R., Leiss & K.A. (2013), The use of bio-guided fractionation to explore the use of leftover biomass in Dutch flower bulb production as allelochemicals against weeds., MOLECULES 18: 4510-4525.
  • Antonio, C., Mustafa, N.R., Osorio, S., Tohge, T., Giavalisco, P., Willmitzer, L., Rischer, H., Oksman-Caldentey, K.M., Verpoorte, R., Fernie & A.R. (2013), Analysis of the interface between primary and secondary metabolism in Catharanthus roseus cell cultures using 13C-stable isotope feeding and coupled mass spectrometry., Molecular Plant 6: 581-584.
  • Mushtaq, M.Y., Verpoorte, R., Kim & H.K. (2013), Zebrafish as a model for systems biology., Biotechnology and Genetic Engineering Reviews .
  • Toyang, N.J., Krause, M., Fairhurst, R., Tane, P., Bryant, J. Verpoorte & R. (2013), Antiplasmodial activity of sesquiterpene lactones and a sucrose ester from Vernonia guineensis Benth., Journal of Ethnopharmacology 147: 618-621.
  • Toyang, N.J., Verpoorte & R. (2013), A Review of the Medicinal Potentials of Plants of the Genus Vernonia., Journal of Ethnopharmacology 146: 681–723.
  • D’Abrosca, B., Scognamiglio, M., Fiumano, V., Esposito, A., Choi, Y.H., Verpoorte, R., Fiorentino & A. (2013), 8. Plant bioassay to assess the effects of allelochemicals on the metabolome of the target species Aegilops geniculata by a NMR-based approach., Phytochemistry 93: 37-40.
  • Lubbe, A., Gude, H., Verpoorte, R., Choi & Y.H. (2013), Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton., Phytochemistry 88: 43-53.
  • Agnolet S., Verpoorte R. & Staerk D. (2012), Comprehensive analysis of commercial willow bark extracts by new technology platform: Combined use of metabolomics, high-performance liquid chromatography-solid-phase-extraction-nuclear magnetic resonance., Journal of Chromatography A 1262: 130-137.
  • Verpoorte R. (2012), Good Practices: The basis for evidence-based medicines., Journal of Ethnopharmacology 140: 455-457.
  • Qin X., Liu N.Q., Li Z., Liu X., Choi Y.H. & Verpoorte R. (2012), Metabolic fingerprinting by 1HNMR for discrimination of the two species used as radix bupleuri., Planta Medica 78: 926-933.
  • Pan Q., Wang Q., Yuan F., Xing S., Zhao J., Choi Y.H., Verpoorte R., Tian Y., Wang G. & Tang K. (2012), Overexpression of ORCA3 and G10H in Catharanthus roseus plants regulated alkaloid biosynthesis and metabolism revealed by NMR-metabolomics., PLoS ONE 7(8): e43038.
  • Ali K., Maltese F., Figueiredo A., Rex M., Fortes A.M., Zyprian E., Pais M.S., Verpoorte R. & Choi Y.H. (2012), lterations in grapevine leaf metabolism upon inoculation with Plasmopara viticola in different time-points., Plant Science 191-192: 100-107.
  • Lubbe A., Verpoorte R. & Choi Y.H. (2012), Metabolomics changes in Narcissus bulbs induced by fungicide applications., Plant Physiology and Biochemistry (Paris) 58: 116-123.
  • El-Seedi H.R., El-Said A., Khalifa S., Goeransson U., Bohlin L., Borg-Karlson A.-K. & Verpoorte R. (2012), Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids., Journal of Agricultural and Food Chemistry 60: 10877-10895.
  • Nuringtyas T.R., Choi Y.H., Verpoorte R., Klinkhamer P.G.L. & Leiss K.A. (2012), Differential tissue distribution of metabolites in Jacobaea vulgaris, Jacobaea aquatica and their crosses., Phytochemistry 78: 89-97.
  • Palama T.L., Grisoni M., Fock-Bastide I., Jade K., Barter L., Choi Y.H., Verpoorte R. & Kodja H. (2012), Metabolome of Vanilla planifolia (Orchidaceae) and related species under Cymbidium mosaic virus (CymMV) infection., Plant Physiology and Biochemistry 60: 25-34.
  • Flores-Sanchez I.J., Choi Y.H. & Verpoorte R. (2012), Metabolite analysis of Cannabis sativa L. by NMR spectroscopy.. In: Kaufmann, M., Klinger, C. (Red.) Functional genomics methods and protocols.: Humana Press. 363-376.
  • Gerardi C., Blando F., Mulé G., Maltese F., Ali K. & Verpoorte R. (2012), Metabolic characterization of Prunus cerasus L. and Prunus mahaleb L. fruit.. In: D'Onghia A., Batlle I., Caruso T., Corelli Grappadelli L., Callesen O., Bonany J. (Red.) XXVIII International Horticultural Congress on Science and Horticulture for People (IHC2010): International Symposium on the Challenge for a Sustainable Production, Protection and Consumption of Mediterranean Fruits and Nuts.. Lisbon, Portugal. 361-368.
  • Lopez-Gresa M.P., Lison P., Kim H.K., Choi Y.H., Verpoorte R., Rodrigo I., Conejero V. & Belles J.M. (2012), Metabolic fingerprinting of Tomato Mosaic Virus infected Solanum lycopersicum., Journal of Plant Physiology 169: 1586-1596.
  • Ali K., Iqbal M., Korthout H.A.A.J., Maltese F., Fortes A.M., Pais M.S., Verpoorte R. & Choi Y.H. (2012), NMR spectroscopy and chemometrics as a tool for anti-TNFa activity screening in crude extracts of grapes and other berries., Metabolomics 8: 1148-1162.
  • Ahmed I.S., El Tobami E.S., Almagboul A.Z. & Verpoorte R. (2012), Characterization of anti-microbial compounds isolated from Mangifera indica L see kernel., University of Africa Journal of Sciences 2: 77-91.
  • Verpoorte R. (2012), Primary data are the basis of all science! Editorial., Journal of Ethnopharmacology 139: 683-684.
  • Saiman M.Z., Mustafa N.R., Schulte A.E., Verpoorte R. & Choi Y.H. (2012), Induction, characterization, and NMR-based metabolic profiling of adventitious root cultures from leaf explants of Gynura procumbens., Plant Cell Tissue and Organ Culture 109: 465-475.
  • Sharma A., Cardoso-Taketa A., Choi Y.H., Verpoorte R. & Villarreal M.L. (2012), A comparison on the metabolic profiling of the Mexican anxiolytic and sedative plant Galphimia glauca four years later., Journal of Ethnopharmacology 141: 964-974.
  • Abreu I.N., Choi Y.H., Sawaya A.C.H.F., Eberlin M.N., Mazzafera P. & Verpoorte R. (2011), Metabolic alterations in different developmental stages of Pilocarpus microphyllus, Planta Med. 77: 293-300.
  • Fortes A.M., Agudelo-Romero P., Silva M.S., Ali K., Sousa L., Maltese F., Choi Y.H., Grimplet J., Martinez-Zapater J.M. & Verpoorte R. (2011), Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening, Onbekend 11: 149.
  • Perrotin-Brunel H., Buijs W., Spronsen J. van, Roosmalen M.J.E. van, Peters C.J., Verpoorte R. & Witkamp G.-J. (2011), Decarboxylation of Delta-9-tetrahydrocannabinol: kinetics and molecular modeling, Onbekend 987: 67-73.
  • Lubbe A. & Verpoorte R. (2011), Cultivation of medicinal and aromatic for specialty industrial materials, Onbekend 59: 785.
  • Palama T.L., Khatib A., Choi Y.H., Come B., Fock I., Verpoorte R. & Kodja H. (2011), Metabolic Characterization of Green Pods from Vanilla planifolia Accessions Grown in La Réunion, Onbekend 72: 258.
  • Kim H.K., Choi Y.H. & Verpoorte R. (2011), NMR-based plant metabolomics: where do we stand, where do we go?, Trends in Biotechnology (Regular edition) 29: 267.
  • Fortes A.M., Pais M.S., Choi Y.H. & Verpoorte R. (2011), Monitoring biochemical changes during grape berry development in Portuguese cultivars by NMR spectroscopy, Food Chemistry 124: 1760.
  • Yuliana N.D., Khatib A., Choi Y.H. & Verpoorte R. (2011), Metabolomics for bioactivity assessment of natural products, Phytotherapy Research 25: 157-169.
  • Kooy F. van der & Verpoorte R. (2011), The Content of Artemisinin in the Artemisia annua Tea Infusion, Planta Medica 77: 1754.
  • Lubbe A., Choi Y.H., Vreeburg P. & Verpoorte R. (2011), Effect of Fertilizers on Galanthamine and Metabolite Profiles in Narcissus Bulbs by 1H NMR, Journal of Agricultural and Food Chemistry 59: 3155.
  • Ali K., Maltese F., Fortes A.M., Salome Pais M., Choi Y.H. & Verpoorte R. (2011), Monitoring biochemical changes during grape berry development in Portuguese cultivars by NMR spectroscopy, Food Chemistry 124: 1760-1769.
  • Mustafa N.R., Winter W. de, Iren F. van & Verpoorte R. (2011), Initiation, growth and cryopreservation of plant cell suspension cultures, Nature Protocols 6: 715-742.
  • Abreu I.N., Choi Y.H., Sawaya A.C.H.F., Eberlin M.N., Mazzafera P. & Verpoorte R. (2011), Metabolic alterations in different developmental stages of Pilocarpus microphyllus, Planta Medica 77: 293.
  • Quintana N., Kooy F. van der, Rhee M.D. van de, Voshol G.P. & Verpoorte R. (2011), Renewable energy from Cyanobacteria: energy production optimization by metabolic pathway engineering, Applied microbiology and biotechnology 91: 471.
  • Choi Y.H., Spronsen J. van, Dai Y., Verberne M., Hollmann F., Arends I.W.C.E., Witkamp G.-J. & Verpoorte R. (2011), Are Natural Deep Eutectic Solvents the missing link in understanding cellular metabolism and physiology?, Plant Physiology 156: 1701.
  • Dao T.T., Linthorst H.J.M. & Verpoorte R. (2011), Chalcone synthase and its functions in plant resistance, Phytochemistry Reviews 10: 397-412.
  • Ali K., Maltese F., Fortes A.M., Pais M.S., Verpoorte R. & Choi Y.H. (2011), Pre-analytical method for NMR-based grape metabolic fingerprinting and chemometrics, Analytica Chimica Acta 703: 179.
  • Mustafa N.R., Winder W. de, Iren F. van & Verpoorte R. (2011), Initiation, growth and cryopreservation of plant cell suspension cultures, Nature Protocols 6: 715.
  • Georgiev M., Ali K., Alipieva K., Verpoorte R. & Choi Y.H. (2011), Metabolic differentiations and classification of Verbascum species, Phytochemistry 72: 2045.
  • Chan W.T., Choi Y.H., Heijden R. van der, Lee M.S., Lin M.K., Kong H., Kim H.K., Verpoorte R., Hankemeier T. & Greef J. van der (2011), Traditional processing strongly affects metabolite composition by hydrolysis in Rehmannia glutinosa Roots, Chemical and pharmaceutical bulletin 59: 546.
  • Yuliana N.D., Iqbal M., Jahangir M., Wijaya C.H., Korthout H.A., Kottenhagen M., Kim H.K. & Verpoorte R. (2011), Screening of selected Asian spices for anti obesity-related bioactivities, Food Chemistry 126: 1724-1729.
  • Yuliana N.D., Khatib A., Verpoorte R. & Choi Y.H. (2011), Comprehensive extraction integrated with NMR metabolomics: a new way of bioactivity screening methods for plants, adenosine A1 receptor binding compounds in Orthosiphon stamineus Benth, Analytical Chemistry 83: 6902.
  • Fischedick J.T., Hazekamp A., Erkelens T., Choi Y.H. & Verpoorte R. (2011), Metabolic fingerprinting of Cannabis sativa L., cannabinoids and terpenoids for chemotaxonomic and drug standardization purposes, Phytochemistry.
  • Maltese F., Ali K., Toepfer R., Choi Y.H. & Verpoorte R. (2011), Metabolic characterization of Palatinate German white wines, Journal of Biomolecular NMR 49: 255.
  • Yuliana N.D., Jahangir M., Korthout H.A., Choi Y.H., Kim H.K. & Verpoorte R. (2011), Comprehensive review on herbal medicine for energy intake suppression, Onbekend 12: 499.
  • Peč J., Flores-Sanchez I.J., Choi Y.H. & Verpoorte R. (2010), Metabolic differentiation of cell suspension cultures of Cannabis sativa L. by 1H-NMR spectroscopy, Biotechnology Letters 32: 935-941.
  • Ali K., Maltese F., Choi Y.H. & Verpoorte R. (2010), Metabolic Constituents of Grapevine and Grape-Derived Products., Phytochem. Rev 9: 357-378.
  • Kim H.K., Wilson E., Choi Y.H. & Verpoorte R. (2010), Metabolomics: A tool for anticancer leadfinding from natural products, Planta Med. 76: 1094-1102.
  • Kim H.K., Saifullah S.K., Wilson E., Prat Kricun S.D., Meissner A., Goraler S., Deelder A.M., Choi Y.H. & Verpoorte R. (2010), Metabolic classification of South-American Ilex Species by NMR-based metabolomics, Phytochemistry 71: 773-784.
  • Verpoorte R., Choi Y.H. & Kim H.K. (2010), Metabolomics: what is new?, Onbekend 25: 128-131.
  • Lubbe A., Pomahacova B., Choi Y.H. & Verpoorte R. (2010), Analysis of metabolic variation and galanthamine content in Narcissus bulbs by 1HNMR., Phytochem. Anal. 21: 66-72.
  • Simoh S., Linthorst H.J.M., Lefeber A.W.M., Erkelens C., Kim H.K., Choi Y.H. & Verpoorte R. (2010), Metabolic changes of Brassica rapa transformed with bacterial isochorismate synthase gene, J. Plant Physiol. 167: 1525-1532.
  • López-Gresa M.P., Maltese F., Bellés J.M., Conejero V., Kim H.K., Choi Y.H. & Verpoorte R. (2010), Metabolic Response of Tomato Leaves upon Different Plant-pathogen Interactions., Phytochem. Anal. 21: 89-94.
  • Flores-Sanchez I.J., Linthorst H.J.M. & Verpoorte R. (2010), In silicio expression analysis of PKS genes isolated from Cannabis sativa L., Onbekend 33: 703-713.
  • Abdel-Farid B., Jahangir M., Mustafa N.R., Dam N. van, Kim H.K., Hondel C.A.M.J.J. van den, Choi Y.H. & Verpoorte R. (2010), Glucosinolate Profiling of Brassica rapa in Response to Infection by Leptosphaeria maculans and Fusarium oxysporum, Onbekend 38: 612-620.
  • Verpoorte R., Choi Y.H. & Kim H.K. (2010), Metabolomics: will it stay?, Phytochem. Anal. 21: 2-3.
  • Rijn R.M. van, Rhee I.K. & Verpoorte R. (2010), Isolation of acetylcholine esterase inhibitory alkaloids from Nerium bowdenii, Onbekend 24: 222-225.
  • Liu N.Q., Cao M., Frédérich M., Choi Y.H., Verpoorte R. & Kooy F. van der (2010), Metabolomic investigation of the ethnopharmacological use of Artemisia afra with NMR Spectroscopy and Multivariate Data Analysis., J. Ethnopharmacol. 128: 230-235.
  • Mirnezhad M., Romero-González R.R., Leiss K.A., Choi H.-K., Verpoorte R. & Klinkhamer P.G.L. (2010), Metabolomic analysis of host plant resistance to thrips in wild and cultivated tomatoes., Phytochem. Anal. 21: 110-117.
  • Khatib A., Wilson E.G., Supardi M. & Verpoorte R. (2010), Isolation of individual hop iso-α-acids stereoisomers by β-cyclodextrin, Food Chemistry 119: 354-357.
  • Maltese F. & Verpoorte R. (2010), Metabolomics: novel tool for studying complex biological systems.. In: Jain S.M., Brar D.S. (Red.) In: Molecular techniques in crop improvement.: Springer Science and Business Media.
  • Verpoorte R. (2010), Overview and Introduction. Comprehensive Natural Products II Chemistry and Biology. Oxford: Elsevier.
  • Shikov A.N., Kundracikova M., Palama T.L., Pozharitskaya O.N., Kosman V.M., Makarov V.G., Galambosi B., Kim H.K., Jang Y.P., Choi Y.H. & Verpoorte R. (2010), Phenolic constituents of Gnaphalium uliginosum., Phytochemistry Letters 3: 45-47.
  • Palama T.L., Menard P., Fock I., Choi Y.H., Bourdon E., Govinden-Soulange J., Bahut M., Payet B., Verpoorte R. & Kodja H. (2010), Shoot differentiation from protocorm callus cultures of Vanilla planifolia (Orchidaceae): proteomic and metabolic responses at early stage, Onbekend 10: 82.
  • Khatib A., Hoek A.C., Jinap S., Sarker Md.Z.I., Jaswir I. & Verpoorte R. (2010), Application of two Dimensional Thin Layer Chromatography Pattern Comparison for fingerprinting the active compounds in the leaves of Vitex trifolia L possessing anti-tracheospasmolytic activity., J. Liq. Chrom. & Rel. Technol. 33: 214-224.
  • Kim H.K., Choi Y.H. & Verpoorte R. (2010), NMR-based metabolomic analysis of plants., Nature Protocols 5: 536-549.
  • Hazekamp A., Fischedick J.T., Diez M.L., Lubbe A., Ruhaak R.L. & Verpoorte R. (2010), Comprehensive Natural Products II Chemistry and Biology. In: Mander L., Lui H-W. (Red.) Chemistry of Cannabis. Oxford: Elsevier. 1033-1084.
  • Liu N.-Q., Choi Y.H., Verpoorte R. & Kooy F. van der (2010), Comparative quantitative analysis of artemisinin with chromatography and qNMR, Phytochem. Anal. 21: 451-456.
  • El-Seedi H.R., El-Barbary M.A., El-Ghorab D.M.H., Bohlin L., Borg-Karlson A.-K., Göransson U. & Verpoorte R. (2010), Recent insights into the biosynthesis and biological activities of natural xanthones., Curr. Med. Chem 17: 854-901.
  • Kim H.K. & Verpoorte R. (2010), Sample preparation for plant metabolomics, Phytochem. Anal. 21: 4-13.
  • Verpoorte R., Frederich M., Delaude C., Angenot L., Dive G., Thepenier P., Jacquier M.-J., Zeches-Hanrot M., Lavaud C. & Nuzillard J.-M. (2010), Moandaensine, a dimeric indole alkaloid from Strychnos moandaensis (Loganiaceae), Phytochemistry Letters 3: 100-103.
  • Palama T.L., Fock I., Choi Y.H., Verpoorte R. & Kodja H. (2010), Biological variation of Vanilla planifolia leaf metabolome., Phytochemistry 71: 567-573.
  • Lubbe A., Khatib A., Yuliana N.D., Jinap S. & Verpoorte R. (2010), Cannabinoid CB1 receptor binding and acetylcholinesterase inhibitory activity of Sceletium tortuosum L., Onbekend 17: 349-355.
  • Jahangir M., Abdel-Farid I.B., Kim H.K., Choi Y.H. & Verpoorte R. (2009), Healthy and unhealthy plants: The effect of stress on the metabolism of Brassicaceae., Environm. Exp. Bot. 67: 23-33.
  • Mustafa N.R., Kim H.K., Choi Y.H., Erkelens C., Lefeber A.W.M., Spijksma G., Heijden R. van der & Verpoorte R. (2009), Retrobiosynthetic investigation of salicylic acid production in Catharanthus roseus cell., Phytochemistry 70: 532-539.
  • Leiss K.A., Maltese F., Choi Y.H., Verpoorte R. & Klinkhamer P.G.L. (2009), Identification of chlorogenic acid as a resistance factor for thrips in chrysanthemum., Plant Physiology 150: 1567-1575.
  • Yuliana N.D., Khatib A., Link-Struensee A.M.R., IJzerman A.P., Rungkat-Zakaria F., Choi Y.H. & Verpoorte R. (2009), Adenosine A1 Receptor Antagonist Activity of Methoxy Flavonoids from Orthosiphon stamineus, Planta Medica 75: 132-136.
  • Kooy F. van der, Pomahacova B. & Verpoorte R. (2009), Cannabis smoke condensate II: The effect of tobacco on tetrahydrocannabinol levels., Inhalation Toxicol. 21: 87-90.
  • Pomahacova B., Kooy F. van der & Verpoorte R. (2009), Cannabis smoke condensate III: The cannabinoid content of vaporised Cannabis sativa., Inhalation Toxicol. 21: 1108-1112.
  • Leiss K.A., Choi Y.H., Abdel-Farid I.B., Verpoorte R. & Klinkhamer P.G.L. (2009), NMR metabolomics of thrips resistance in Senecio hybrid., J. Chem. Ecol. 35: 219-229.
  • Khatib A., Yuliana N.D., Jinap S., Sarker Md.Z.I., Jaswir I., Wilson E.G., Chung S.K. & Verpoorte R. (2009), Identification of possible compounds possessing adenosine A1 receptor binding activity in the leaves of Orthosiphon stamineus using TLC and mulitivariate data analysis., J. Liq. Chrom. & Rel. Technol. 32: 2906-2916.
  • Romero-González R. & Verpoorte R. (2009), Salting-out gradients in centrifugal partition chromatography for the isolation of chlorogenic acids from green coffee beans., J. Chromatogr. A. 1216: 4245-4251.
  • Simoh S., Quintana N., Kim H.K., Choi Y.H. & Verpoorte R. (2009), Metabolic changes in Agrobacterium tumefaciens –infected Brassica rapa., J. Plant Physiol. 166: 1005-1014.
  • Kooy F. van der, Maltese F., Choi Y.H., Kim H.K. & Verpoorte R. (2009), Quality control of herbal material and phytopharmaceuticals with the use of MS and NMR based metabolic fingerprinting., Planta Med. 75: 763-775.
  • Mustafa N.R., Kim H.K., Choi Y.H. & Verpoorte R. (2009), Metabolic changes of salicylic acid-elicited Catharanthus roseus cell suspension cultures monitored by NMR-based metabolomics, Biotechnol. Lett. 31: 1967-1974.
  • Jahangir M., Kim H.K., Choi Y.H. & Verpoorte R. (2009), Health affecting compounds in Brassicaceae., Compr. Rev. Food Sci. Food Safety 8: 31-43.
  • Palama T.L., Khatib A., Choi Y.H., Fock I., Payet B., Verpoorte R. & Kodja H. (2009), Metabolic changes in different developmental stages of Vanilla planifolia pods, J. Agricult. Food Chem. 57: 7651-7658.
  • Flores-Sanchez I.J. & Verpoorte R. (2009), Plant polyketide synthases: a fascinating group of enzymes., Plant Physiol. Biochem. 47: 167-174.
  • Pomahacova B., Dusek J., Dusková J., Yazaki K., Roytrakul S. & Verpoorte R. (2009), Improved accumulation of ajmalicine and tetrahydroalstonine in Catharanthus cells expressing an ABC transporter., J. Plant Physiol. 166: 1405-1412.
  • Maltese F., Erkelens C., Kooy F. van der, Choi Y.H. & Verpoorte R. (2009), Identification of natural enantiomeric flavanone glycosides by NMR spectroscopy., Food Chemistry 116: 575-579.
  • Rashidi H., Akhtar M.T., Kooy F. van der, Verpoorte R. & Duetz W.A. (2009), Hydroxylation and further oxidation of Δ9-tetrahydrocannabinol by alkane degrading bacteria., Appl. Environm. Microbiol. 75: 7135-7141.
  • Mosley Arany A., Jong T.J. de, Kim H.K., Dam N.M. van, Choi Y.H., Mil H.G.J. van, Verpoorte R. & Meijden E. van der (2009), Genotype-environment interactions affect flower and fruit herbivory and plant chemistry of Arabidopsis thaliana in a transplant experiment., Ecol. Res. 21: 1161-1171.
  • Hien Dao T.T., Puig R.C., Kim H.K., Erkelens C., Lefeber A.W., Linthorst H.J.M., Choi Y.H. & Verpoorte R. (2009), Effect of benzothiadiazole on the metabolome of Arabidopsis thaliana., Plant Physiology and Biochemistry 47: 146-152.
  • Arany A.M., Jong T.J. de, Kim H.K., Dam N.M. van, Choi Y.H., Mil H.G.J. van, Verpoorte R. & Meijden E. van der (2009), Genotype-environment interactions affect flower and fruit herbivory and plant chemistry of Arabidopsis thaliana in a transplant experiment., Ecological Research 24: 1161-1171.
  • Flores-Sanchez I.J., Peč J., Fei J., Choi Y.H., Dusek J. & Verpoorte R. (2009), Elicitation studies in cell suspension cultures of Cannabis sativa L., J. Biotechnol. 143: 157-168.
  • Maltese F., Kooy F. van der & Verpoorte R. (2009), Solvent Derived Artifacts in Natural Products Chemistry, Nat. Prod. Commun. 4: 447-454.
  • Fortes A.M., Batista D., Santos F., Figueiredo A., Serrazina S., Choi Y.H., Miersch O., Lange P., Wasternack C., Verpoorte R. & Pais M.S. (2009), Deciphering morphogenesis for hop improvement. A transcriptomic and metabolomic perspective.. In: Proceedings of the Scientific Commission International Hop Growers' Convention (I.H.G.C.). Leon. 35-40.
  • Fischedick J.T., Glas R., Hazekamp A. & Verpoorte R. (2009), A Qualitative and Quantitative HPTLC Densitometry Method for the Analysis of Cannabinoids in Cannabis sativa L., Phytochem. Anal. 20: 421-426.
  • El-Seedi H.R., El-Ghorab D.M.H., El-Barbary M.A., Zayed M.F., Goeransson U., Larsson S. & Verpoorte R. (2009), Naturally occurring xanthones; latest investigations: isolation, structure elucidation and chemosystematic significance., Curr. Med. Chem 16: 2581-2626.
  • Dayakar V., Badri N., Quintana N., El Kassis E., Kim H.K., Choi Y.H., Suguyama A., Verpoorte R., Martinoia E., Manter D.K. & Vivanco Jorge M. (2009), An ABC transporter mutation alters in root exudation of phytochemicals that provoke an overhaul of natural soil microbiota., Plant Physiol. 151: 2006-2017.
  • Abdel-Farid I.B., Jahangir M., Hondel C.A.M.J.J. van den, Kim H.K., Choi Y.H. & Verpoorte R. (2009), Fungal infection-induced metabolites in Brassica rapa., Plant Science 176: 608-615.
  • Ali K., Maltese F., Zyprian E., Rex M., Choi Y.H. & Verpoorte R. (2009), NMR metabolic fingerprinting based identification of grapevine metabolites associated with downy mildew resistance., J. Agricult. Food Chem. 57: 9599-9606.
  • Angelova N.S., Kong H.W., Heijden R. van der, Yang S.Y., Choi Y.H., Kim H.K., Wang M., Hankemeier T., Greef J. van der, Xu X. & Verpoorte R. (2008), Recent methodology in the phytochemical analysis of ginseng, Phytochemical Analysis 19: 2-16.
  • Figueiredo A.C., Fortes M., Ferreira S., Sebastiana M., Choi Y.H., Sousa L., Acioli-Santos B., Pessoa F., Verpoorte R. & Salomé Pais M. (2008), Transcriptional and metabolic profiling of grape (Vitis vinifera L.) leaves unravel possible innate resistance against pathogenic fungi, J. Exp. Bot. 59: 3371-3381.
  • Verpoorte R., Choi Y.H., Mustafa N.K. & Kim H.K. (2008), Metabolomics: back to basics, Phytochemistry Reviews 7: 525-538.
  • Maltese F. & Verpoorte R. (2008), Metabolomics: novel tool for studying complex biological systems. In: M. Jain (Red.) Metabolomics: novel tool for studying complex biological systems.
  • Verpoorte R. (2008), Medicinal plants: a renewable resource for novel leads and drugs. In: K.G. Ramawat (Red.) Herbal Drugs: Ethnomedicine to Modern Medicine. Berlin Heidelberg: Springer. 1-5.
  • Verpoorte R. (2008), Medicinal plants: a renewable resource for novel leads and drugs Herbal drugs: Ethnomedicine to modern medicine. In: K.G. Ramawat (Red.) Ethnomedicine to modern medicine: Springer.
  • Jahangir M., Abdel-Farid I.B., Choi Y.H. & Verpoorte R. (2008), Metal ions-inducing Metabolites Accumulation in Brassica rapa, Journal of Plant Physiology 165: 1429-1437.
  • Mustafa N.R., Kim H.K., Choi Y.H., Erkelens C., Lefeber A.W.M., Spijksma G., Heijden R. van der & Verpoorte R. (2008), Retrobiosynthetic investigation of salicylic acid production in Catharanthus roseus cell, Phytochemistry.
  • Verpoorte R. (2008), Repository for ethnopharmacological survey data, Journal of Ethnopharmacology 120: 127-128.
  • Abdel-Farid I.B., Choi Y.H., Kim H.K., Hondel C.A.M.J.J. van den, Meijden E. van der & Verpoorte R. (2008), The role of secondary metabolites in Arabidopsis and Brassica in the interaction with fungi, Current Topics in Microbiology and Immunology.
  • Mustafa N.K., Kim H.K., Choi Y.H. & Verpoorte R. (2008), Single step purification of salicylic acid from Catharanthus roseus cell culture (plant material) by anion exchange for NMR analysis, Journal of Liquid Chromatography and Related Technologies 31: 702-713.
  • Simoh S., Quintana N., Kim H.K., Choi Y.H. & Verpoorte R. (2008), Metabolic changes in Agrobacterium tumefaciens –infected Brassica rapa, Journal of Plant Physiology.
  • Fraccaroli M., Nicoletti S., Maltese F., Choi Y.H., Guzzo F., Levi M. & Verpoorte R. (2008), Preanalytical method for metabolic profiling of plant cell cultures of Passiflora garckei, Biotechnology Letters.
  • Fortes A., Santos F., Choi Y.H., Figueiredo A.C., Silva M.S., Sousa L., Pessoa F., Acioli B., Sebastiana M., Palme K., Malhó R., Verpoorte R. & Pais M.S. (2008), Organogenic nodule development in hop (Humulus lupulus L.): transcript and metabolic responses, BMC Genomics 9: 445.
  • Ali K., Maltese F., Choi Y.H. & Verpoorte R. (2008), Metabolic Constituents of Grapevine and Grape-Derived Products, Journal of Food Science.
  • Jahangir M., Bayoumi I., Abdel-Farid I.B., Kim H.K., Choi Y.H. & Verpoorte R. (2008), Stress induced metabolic responses in food plants of Brassicaceae, Mol. Biosystem..
  • Chang W.T., Choi Y.H., Heijden R. van der, Kong H., Kim H.K., Verpoorte R., Xu G., Hankemeier T., Greef J. van der & Wang M. (2008), Traditional processing strongly affects metabolite composition by hydrolysis in Rehmannia glutinosa Roots, Journal of Ethnopharmacology.
  • Leiss K.A., Choi Y.H., Abdel-Farid I.B., Verpoorte R. & Klinkhamer P.G.L. (2008), NMR metabolomics of thrips resistance in Senecio hybrid, Journal of Chemical Ecology.
  • Zárate R. & Verpoorte R. (2008), Metabolic Engineering of Plant Cellular Metabolism: Methodology, Advances and Future Directions. In: W. Zhang (Red.) Progress in Bioproducts and Biotechnological Applications: Springer.
  • Flores-Sanchez I.J. & Verpoorte R. (2008), Secondary metabolism in Cannabis, Phytochem. Rev 7: 615-639.
  • Verpoorte R. (2008), Setting standards: diabetes, Journal of Ethnopharmacology 115: 161-162.
  • El-Seedi H.R., El-Ghorab D.M.H., El-Barbary M.A., Larsson S. & Verpoorte R. (2008), Naturally occurring xanthones; latest investigations: isolation, structure elucidation and chemosystematic significance, Curr. Med. Chem.
  • Kooy F. van der, Maltese F., Choi Y.H., Kim H.K. & Verpoorte R. (2008), Quality control of herbal material and phytopharmaceuticals with the use of MS and NMR based metabolic fingerprinting, Planta Medica.
  • Fraccaroli M., Nicoletti S., Maltese F., Choi Y.H., Guzzo F., Levi M. & Verpoorte R. (2008), Preanalytical method for metabolic profiling of plant cell cultures of Passiflora garcke, Biotechnology Letters 30: 2031-2035.
  • Kooy F. van der, Verpoorte R. & Meyer J.J.M. (2008), Metabolomic quality control of claimed anti-malarial Artemisia afra herbal remedy and A. afra and A. annua plant extracts, South African J. Bot. 74: 186-189.
  • Flores-Sanchez I.J. & Verpoorte R. (2008), Plant polyketide synthases: a fascinating group of enzymes, Plant Physiology and Biochemistry.
  • Taketa A.T.C., Pereda-Miranda R., Choi Y.H., Verpoorte R. & Villarreal M.L. (2008), Metabolomic profiling of the Mexican anxiolytic and sedative plant Galphimia glauca using nuclear magnetic resonance spectroscopy and multivariate data analysis, Planta Medica 74: 1295-1301.
  • Jahangir M., Kim H.K., Choi Y.H. & Verpoorte R. (2008), Metabolomic response of Brassica rapa submitted to pre-harvest bacterial contamination, Food Chemistry 107: 362-368.
  • Abreu I.N., Choi Y.H., Sawaya A.C.H.F., Eberlin M.N., Marcos N., Mazzafera P. & Verpoorte R. (2008), Metabolic alterations in different developmental stages of Pilocarpus microphyllus, Planta.
  • Abdel-Farid I.B., Jahangir M., Mustafa N.R., Dam N. van, Hondel C.A.M.J.J. van den, Kim H.K., Choi Y.H. & Verpoorte R. (2008), Glucosinolate Profiling of Brassica rapa in Response to Infection by Leptosphaeria maculans and Fusarium oxysporum, Journal of Liquid Chromatography and Related Technologies.
  • Abdel-Farid I.B., Jahangir M., Kim H.K., Choi Y.H. & Verpoorte R. (2008), Fungal infection-induced metabolites in Brassica rapa, Plant Science.
  • Jahangir M., Kim H.K., Choi Y.H. & Verpoorte R. (2008), Health affecting compounds in Brassicaceae, Compr. Rev. Food Sci. Food Safety.
  • Simoh S., Linthorst H.J.M. & Verpoorte R. (2008), Host-bacterium interactions in Agrobacterium tumefaciens-mediated plant transformation: Mechanism of action and Agrobacterium/plant factors involved, Plant Biology 8: 1-20.
  • Sumthong P., Romero-Gonzalez R.R. & Verpoorte R. (2008), Identification of Anti-Wood Rot Compounds in Teak (Tectona grandis L.f.) Sawdust Extract, Wood Chem. Technol. 28: 247-260.
  • Ridder S. de, Kooy F. van der & Verpoorte R. (2008), Artemisia annua as a self-reliant treatment for malaria in developing countries, Journal of Ethnopharmacology 120: 302-314.
  • Flores-Sanchez I.J., Peč J., Fei J., Choi Y.H., Dusek T.J. & Verpoorte R. (2008), Elicitation studies in cell suspension cultures of Cannabis sativa L, Plant Biotechnology Journal.
  • Verpoorte R., Crommelin D.J.A., Danhof M., Gilissen L.J., Schuitmaker H., Greef J. van der & Witkamp R.F. (2008), Commentary: "A systems view on the future of medicine: Inspiration from Chinese medicine?", Journal of Ethnopharmacology.
  • Dao T.H.H., Puig R.C., Kim H.K., Erkelens C., Lefeber A.W.M., Linthorst H.J.M., Choi Y.H. & Verpoorte R. (2008), Effect of benzothiadiazole on the metabolome of Arabidopsis thaliana, Plant Physiology and Biochemistry.
  • Mosleh Arany A., Jong T.J. de, Kim H.K., Dam N. van, Choi Y.H., Verpoorte R. & Meijden E. van der (2008), Different chemical composition of plants from dune and inland populations of Arabidopsis thaliana in the Netherlands and their implications for plan-herbivore interactions, Journal of Chemical Ecology.
  • Zuurman L., Roy C., Schoemaker R.C., Hazekamp A., Den Hartigh J., Bender J.C.M.E., Verpoorte R., Pinquier J., Cohen A.F. & Gerven J.M.A. van (2008), Effect of intrapulmonary tetrahydrocannabinol administration in humans, Journal of Psychopharmacology 22: 707-716.
  • Škrlep K., Bergant M., Winter G.M., Bohanec B., Žel J., Verpoorte R., Iren F. van & Camloh M. (2008), Cryopreservation of cell suspension cultures of yew: Taxus x media Rehd. and Taxus floridana, Plant Cell Tissue and Organ Culture.
  • Škrlep K., Bergant M., Winter G.M., Bohanec B., Žel J., Verpoorte R., Iren F. van & Camloh M. (2008), Cryopreservation of cell suspension cultures of Taxus × media and Taxus floridana, Biologia Plantarum 52: 329-333.
  • Maltese F., Erkelens C., Kooy F. van der, Choi Y.H. & Verpoorte R. (2008), Identification of natural enantiomeric flavanone glycosides by NMR spectroscopy, J. Nat. Prod..
  • Mosleh Arany A., Jong T.J. de, Kim H.K., Dam N. van, Choi Y.H., Verpoorte R. & Meijden E. van der (2008), Glucosinolates and other metabolites in leaves of Arabidopsis thaliana from natural populations and their effects on a generalist and a specialist Herbivore, Journal of Chemical Ecology 18: 65-71.
  • Flores-Sanchez I.J. & Verpoorte R. (2008), Activities and Biosynthesis of Cannabinoids and Flavonoids in Cannabis sativa L. Plants, Plant and Cell Physiology 49(12): 1767-1782.
  • Yuliana N.D., Khatib A., Link-Struensee A.M.R., IJzerman A.P., Choi Y.H. & Verpoorte R. (2008), Adenosine A1 Receptor Antagonist Activity of Methoxy Flavonoids from Orthosiphon stamineus, Planta Medica.
  • Karlsson P., Pettersson J., Choi Y.H., Verpoorte R., Bohlin L. & Rafter J.J. (2008), A NMR metabolomic method for the identification of dietary anti-inflammatory compounds in fecal water, Biological Pharmaceutical Bulletin 31: 1192-1198.
  • Hazekamp A., Bastola K., Rashidi H., Bender J. & Verpoorte R. (2007), Cannabis tea revisited: A systematic evaluation of the cannabinoid composition of cannabis tea, Journal of Ethnopharmacology 113: 85-90.
  • Sanchez-Sampredo A., Kim H.K., Choi Y.H., Verpoorte R. & Corchete P. (2007), Metabolomic alterations in elicitor treated Silybum marianum suspension cultures monitored by nuclear magnetic resonance spectroscopy, Journal of Biotechnology 130: 133-142.
  • Mustafa N.R.. & Verpoorte R. (2007), Phenolic compounds in Catharanthus roseus, Phytochemistry Reviews 6: 243-258.
  • Abdel-Farid I.B., Kim H.K., Choi Y.H. & Verpoorte R. (2007), Metabolic characterization of Brasica rapa leaves by NMR-spectroscopy, Journal of Agricultural and Food Chemistry 55: 7936-7943.
  • El-Sayed M. & Verpoorte R. (2007), Catharanthus terpenoid indole alkaloids: biosynthesis and regulation, Phytochemistry Reviews 6: 277-305.
  • Verpoorte R. (2007), Introduction. In: R. Verpoorte, A.W. Alfermann and T.S. Johnson (Red.) Applications of plant metabolic engineering. Dordrecht: Springer. XI-XXI.
  • Korthout H.A. & Verpoorte R. (2007), Vanilla. In: Flavours and Fragrances. Chemistry, Bioprocessing and Sustainability. Berlin: Springer-Verlag. 203-217.
  • Roytrakul S. & Verpoorte R. (2007), Role of vacuolar transporter proteins in plant secondary metabolism: Catharanthus roseus cell culture, Phytochemistry Reviews 6: 383-396.
  • Khatib A., Wilson E.G., Kim H.K., Supardi M., Choi Y.H. & Verpoorte R. (2007), NMR assignment of iso--acids from isomerised extracts of Humulus lupulus L. cones, Phytochemical Analysis 18: 371-377.
  • Verpoorte R., Choi Y.H. & Kim H.K. (2007), NMR-based metabolomics at work in phytochemistry, Phytochemistry Reviews 6: 3-14.
  • El-Seedi H.R., El-Hamid N.S.A., Goransson U. & Verpoorte R. (2007), Cyclopeptide alkaloids, Phytochemistry Reviews 6: 143-165.
  • Verberne M.C., Sansuk K., Bol J.F., Linthorst H.J.M. & Verpoorte R. (2007), Vitamin K1 accumulation in tobacco plants overexpressing bacterial genes involved in the biosynthesis of salicylic acid, Journal of Biotechnology 128: 72-79.
  • Zarate R. & Verpoorte R. (2007), Strategies for the Genetic Modification of the Medicinal Plant Catharanthus roseus (L.) G. Don., Phytochemistry Reviews 6: 475-491.
  • Bastola K., Hazekamp A. & Verpoorte R. (2007), Synthesis and spectroscopic characterization of cannabinolic acid, Planta Medica 73: 273-275.
  • Verberne M.C., Sansuk K., Bol J.F., Linthorst H.J.M. & Verpoorte R. (2007), Vitamin K1 accumulation in tobacco plants overexpressing bacterial genes involved in the biosynthesis of salicylic acid, Journal of Biotechnology 128: 72-79.
  • Zhao J. & Verpoorte R. (2007), Manipulating indole alkaloid production by Catharanthus roseus cell cultures in bioreactors: From biochemical processing to metabolic engineering, Phytochemistry Reviews 6: 435-457.
  • Widarto H.T., Meijden E. van der, Lefeber A.W.M., Erkelens C., Kim H.K., Choi Y.H. & Verpoorte R. (2006), Metabolomic differentiation of Brassica rapa following herbivory by different insect instars using two dimensional nuclear magnetic resonance spectroscopy, Journal of Chemical Ecology 32(11): 2417-2428.
  • Widarto H.T., Meijden E. van der, Lefeber A.W.M., Erkelens C., Kim H.K., Choi Y.H. & Verpoorte R. (2006), Metabolomic differentiation of Brassica rapa leaves attacked by herbivore using two dimensional nuclear magnetic resonance spectroscopy, Journal of Chemical Ecology 32: 2417-2428.
  • Liang Y.-S., Choi Y.H., Kim H.K., Linthorst H.J.M. & Verpoorte R. (2006), Metabolomic analysis of methyl jasmonate treated Brassica rapa leaves by 2-dimensional NMR spectroscopy, Phytochemistry 67: 2503-2511.
  • Kim H.K., Choi Y.H. & Verpoorte R. (2006), Metabolomic analysis of Catharanthus roseus using NMR and principal component analysis. Biotechnology. In: Saito K., Dixon R., Willmitzer L. (Red.) Agriculture and Forestry. Heidelberg: Springer. 261-276.
  • Choi Y.H., Kim H.K. & Verpoorte R. (2006), Metabolomics. In: Kayser O, Quax W (Red.) Medicinal Plant Biotechnology: From Basic Research to Industrial Applications. Weinheim: Wiley-VCH. 9-28.
  • El-Seedi H.R., El-Hamid N.S.A., Goransson U. & Verpoorte R. (2006), Cyclopeptide alkaloids, Phytochemistry Reviews.
  • Choi Y.H., Kim H.K., Verpoorte R., Linthorst H.J.M., Hollander J., Lefeber A.W.M., Erkelens C. & Nuzillard J.-M. (2006), NMR metabolomics to revisit the tobacco mosaic virus infection in Nicotiana tabacum leaves, Journal of Natural Products 69: 742-742.
  • Verberne M.C., Sansuk K., Bol J.F., Linthorst H.J.M. & Verpoorte R. (2006), Vitamin K1 accumulation in tobacco plants overexpressing bacterial genes involved in the biosynthesis of salicylic acid, Plant Physiology 29: 293-302.
  • Hazekamp A., Ruhaak R., Zuurman L., Gerven J.M.A. van & Verpoorte R. (2006), Evaluation of a vaporizing device (Volcano) for the pulmonary administration of tetrahydrocannabinol, Journal of Pharmaceutical Sciences 95: 1308-1317.
  • Thongphasuk P., Suttisri R., Bavovada R. & Verpoorte R. (2006), Two new pimarane diterpenoids from Strychnos vanprukii Craib, Journal of Asian Natural Products Research 20: 966-968.
  • Verpoorte R. & Hoopen H.J.G. ten (2006), Plant Cell Biotechnology. In: Ratledge C., Kristiansen B. (Red.) Basic Biotechnology. Cambridge: Cambridge University Press. 549-577.
  • Liang Y.-S., Choi Y.H., Kim H.K., Linthorst H.J.M. & Verpoorte R. (2006), Metabolomic analysis of methyl jasmonate treated Brassica rapa leaves by two dimensional NMR spectroscopy and multivariate analysis, Phytochemistry 67: 2503-2511.
  • Hendrawati O., Yao Q., Kim H.K., Linthorst H.J.M., Erkelens C., Lefeber A.W.M., Choi Y.H. & Verpoorte R. (2006), Metabolic differentiation of Arabidopsis treated with methyl jasmonate using nuclear magnetic resonance spectroscopy, Plant Science 170: 1118-1124.
  • Hendrawati O., Yao Q., Choi Y.H., Kim H.K., Linthorst H.J.M., Erkelens C., Lefeber A.W.M. & Verpoorte R. (2006), Metabolic differentiation of Arabidopsis treated with methyl jasmonate using nuclear magnetic resonance spectroscopy, Plant Science 170: 1118-1124.
  • Khatib A., Kim H.K., Wilson E.G., Choi Y.H. & Verpoorte R. (2006), High performance liquid chromatographic method for iso-alpha-acids, Journal of Liquid Chromatography and Related Technologies 29: 293-302.
  • Yang S.Y., Kim H.K., Lefeber A.W.M., Erkelens C., Angelova N.S., Choi Y.H. & Verpoorte R. (2006), Application of Two Dimensional Nuclear Magnetic Resonance Spectroscopy to Quality Control of Ginseng Commercial Products, Planta Medica 72: 364-369.
  • Trevisan M.T.S., Barbosa Bezerra M.Z., Pinheiro Santiago G.M., Mendes Feitosa C., Verpoorte R. & Braz Filho R. (2006), Atividades larvacida e anticolinesterasica de plantas do genero Kalanchoe Quim, Nova 29: 415-418.
  • Sumthong P., Damveld R.A., Choi Y.H., Arentshorst M., Ram A.F.J., Hondel C.A.M.J.J. van den & Verpoorte R. (2006), Activity of quinones from teak (Tectona grandis) on fungal cell wall stress, Planta Medica 72: 943-944.
  • Liang Y.-S., Lefeber A.W.M., Erkelens C., Kim H.K., Choi Y.H. & Verpoorte R. (2006), Identification of phenylpropanoids in Brassica rapa leaves treated with methyl jasmonate using two-dimensional nuclear magnetic resonance spectroscopy, Journal of Chromatography A 1112: 148-155.
  • Sumthong P., Damveld R.A., Choi Y.H., Arentshorst M., Ram A.F.J., Hondel C.A.M.J.J. van den & Verpoorte R. (2006), Activity of quinones from teak (Tectona grandis) on fungal cell wall stress, Planta Medica 72: 943-944.
  • Hazekamp A. & Verpoorte R. (2006), Structure elucidation of the tretrahydrocannabinol complex with randomly methylated Beta-cyclodextrin, European Journal of Pharmaceutical Sciences 29: 340-347.
  • Verpoorte R. (2006), Application of Two Dimensional Nuclear Magnetic Resonance Spectroscopy to Quality Control of Ginseng Commercial Products, Planta Medica 72: 364-369.
  • Khatib A., Wilson E.G., Kim H.K., Lefeber A.W.M., Erkelens C., Choi Y.H. & Verpoorte R. (2006), Application of two dimensional J-resolved nuclear magnetic resonance spectrum to differentiation of beer, Analytica Chimica Acta 559: 264-270.
  • Mosleh Arany A., Jong T.J. de, Kim H.K., Dam N. van, Choi Y.H., Verpoorte R. & Meijden E. van der (2006), Glucosionaltes and some other chemical compounds in natural populations of Arabidopsis thaliana and their effects on generalist and specialist herbivores, Journal of Chemical Ecology.
  • Kirk H.E., Choi Y.H., Kim H.K., Verpoorte R. & Meijden E. van der (2005), Comparing metobolomics: the chemical consequences of hybridization in plants, New Phytology: 613-622.
  • Kirk H.E., Choi Y.H., Kim H.K., Verpoorte R. & Meijden E. van der (2005), Comparing metabolomes: the chemical consequences of hybridization in plants, New Phytology 167: 613-622.
  • Hazekamp A., Serier P., Verpoorte R., Bender J. & Bakel N. van (2005), Cannabis uit de apotheek is beter, Pharmaceutisch Weekblad 140: 402-404.
  • Rauter A.P., Martins A., Borges C., Ferreira J., Justino J., Bronze M.R., Coelho A.V., Choi Y.H. & Verpoorte R. (2005), Liquid Chromatography-diode array detection-electronspray ionisation mass spectrometry/nuclear magentic resonance analyses of the anti-hyperglemic flavonoid extract of Genista tenera structure elucidation of a flavonoid-C-glycoside, Journal of Chromatography A 1089: 59-64.
  • Wang M., Lamers R.J., Korthout H.A., Nesselrooij J.H. van, Witkamp R.F., Heijden R. van der, Voshol P.J., Havekes L.M., Verpoorte R. & Greef J. van der (2005), Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology., Phytotherapy Research 19(3): 173-182.
  • Verpoorte R., Kim H.K. & Choi Y.H. (2005), Editorial, Journal of Ethnopharmacology 100: 53-56.
  • El-Sayed M. & Verpoorte R. (2005), Methyljasmonate accelerates catabolism of monoterpenoid indole alkaloids in Catharanthus roseus during leaf processing, Fitoterapia 76: 83-90.
  • Iren F. van, Winter W. de, Roytrakul S., Choi Y.H., Verpoorte R. & Suhartono L. (2005), Metabolic comparison of cryopreserved and normal cells from Tabernaemontana divaricata suspension cultures, Plant Cell Tissue and Organ Culture 83: 59-66.
  • Wang M., Lamers R.J., Korthout H.A., Nesselrooij J.H. van, Witkamp R.F., Heijden R. van der, Voshol P.J., Havekes L.M., Verpoorte R. & Greef J. van der (2005), Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology., Phytotherapy Research 19(3): 173-182.
  • Hazekamp A., Peltenburg A., Verpoorte R. & Giroud C. (2005), Chromatographic and spectroscopic data of cannabinoids from Cannabis sativa L, Journal of Liquid Chromatography and Related Technologies 28: 2361-2382.
  • Kim H.K., Choi Y.H., Erkelens C., Lefeber A.W.M. & Verpoorte R. (2005), Metabolic fingerprinting of Ephedra species using 1H-NMR spectroscopy and principle component analysis, Chemical and pharmaceutical bulletin 53: 105-109.
  • Jacobs D.I., Gaspari M., Greef J. van der, Heijden R. van der & Verpoorte R. (2005), Proteome analysis of the medicinal plant Catharanthus roseus, Planta 221: 690-704.
  • Verpoorte R., Kim H.K. & Choi Y.H. (2005), New perspectives of medicinal plants in a globalized world. In: Mukherjee P.K. (Red.) Proceedings International Conference on Botanicals. Kolkata, India: Allied Book Agency. 11-18.
  • Canto-Canche B.B., Meijer A.H., Collu G., Verpoorte R. & Loyola-Vargas V.M. (2005), Characterization of a polyclonal antiserum against the monoterpene monooxygenase, geraniol 10-hydroxylase from Catharanthus roseus, Journal of Plant Physiology 162: 393-402.
  • Choi Y.H., Sertic S., Kim H.K., Wilson E.G., Michopoulosa F., Lefeber A.W.M., Erkelens C., Kricun S.D.P. & Verpoorte R. (2005), Classification of Ilex species based on metabolomic fingerprinting using NMR and multivariate data analysis, Journal of Agricultural and Food Chemistry 53: 1237-1245.
  • Verpoorte R. (2005), Ethnopharmacology and systems biology: a perfect holistic match, Journal of Ethnopharmacology 100: 1-2.
  • Dignum M.J.W. & Verpoorte R. (2005), Enzymes in curing vanilla. In: Frenkel D. (Red.) Vanilla.
  • Zhao J., Davis L.C., Tang X. & Verpoorte R. (2005), Elicitor Signal Transduction Leading to Production of Plant Secondary Metabolites, Biotechnology advances 23: 283-333.
  • Jacobs D.I., Gaspari M., Greef J. van der, Heijden R. van der & Verpoorte R. (2005), Proteome analysis of Catharanthus roseus cultured cells for the identification of proteins involved in alkaloid biosynthesis and finding of novel sequences, Planta 221: 690-704.
  • Raharjo T.J., Chang W.T., Choi Y.H., Peltenburg-Looman A.M.G. & Verpoorte R. (2004), Olivetol as product of a polyketide synthase (PKS) in Cannabis sativa, Plant Science 166: 381-385.
  • Hazekamp A., Simons R., Peltenburg-Looman A.M.G., Sengers M., Zweden R. van & Verpoorte R. (2004), Preparative isolation of cannabinoids from Cannabis sativa by centrifugal partitioning chromatography, J. Liq. Chrom. & Rel. Technol. 27: 2421-2440.
  • Raharjo T.J., Chang W.T., Verberne M.C., Peltenburg-Looman A.M.G. & Verpoorte R. (2004), Cloning and overexpression of a cDNA encoding a polyketide sythase (PKS) from Cannabis sativa L, Plant Physiology and Biochemistry 42: 291-297.
  • Frederich M., Cristino A., Choi Y.H., Verpoorte R., Tits M., Angenot L. & Zeches-Hanrot M. (2004), Chrysopentamine an antiplasmodial anhydronium base from Strychnos usambarensis, Planta Medica 70: 72-76.
  • Choi Y.H., Kim H.K., Wilson E., Erkelens C., Trijzelaar B. & Verpoorte R. (2004), Quantitative analysis of retinol and retinol palmitate in vitamin tablets using 1H-nuclear magnetic resonance spectroscopy, Analytica Chima Acta 512: 141-147.
  • Raharjo T.J., Chang W.T., Verberne M.C., Peltenburg-Looman A.M.G., Linthorst H.J.M. & Verpoorte R. (2004), Cloning and over-expression of a cDNA encoding a polyketide synthase from Cannabis sativa, Plant Physiology and Biochemistry 42: 291-297.
  • Choi Y.H., Choi H.-K., Peltenburg-Looman A.M.G., Lefeber A.W.M. & Verpoorte R. (2004), Quantitative analysis of ginkgolic acids from Ginkgo leaves and products using 1HNMR, Phytochemical Analysis 15: 325-330.
  • Heijden R. van der, Jacobs D.I., Snoeijer W., Hallard D. & Verpoorte R. (2004), Catharanthus roseus alkaloids: Pharmacognosy and biotechnology, Current Medicinal Chemistry 11: 1241-1253.
  • Choi Y.H., Hazekamp A., Peltenburg-Looman A.M.G., Frederich M., Erkelens C., Lefeber A.W.M. & Verpoorte R. (2004), NMR Assignment of major cannabinoids and cannbiflavonoids isolated from Cannabis sativa flowers, Phytochemical Analysis 15: 345-354.
  • Dignum M., Heijden R. van der, Kerler J., Winkel C. & Verpoorte R. (2004), Identification of glucosides in green beans of Vanilla planifolia Andrews and kinetics of vanilla beta-glucosidase, Food Chemistry 85: 199-205.
  • Choi Y.H., Casas Tapias E., Kim H.K., Lefeber A.W.M., Erkelens C., Verhoeven J.TH.J., Brzin J., Zel J. & Verpoorte R. (2004), Metabolic discrimination of Catharanthus roseus leaves infected by phytoplasma using 1HNMR spectroscopy and multivariate data analysis, Plant Physiology 135: 2398-2410.
  • Raharjo T.J. & Verpoorte R. (2004), Methods for cannabinoids analysis in biological materials, Phytochemical Analysis 15: 79-94.
  • Choi H.-K., Choi Y.H., Verberne M., Lefeber A.W.M., Erkelens C. & Verpoorte R. (2004), Metabolic fingerprinting of wild type and transgenic tobacco plants by 1H NMR and multivariate analysis technique, Phytochemistry 65: 857-864.
  • Chatzimichalakis P.F., Samanidou V.F., Verpoorte R. & Papadoyannis I.N. (2004), Development of a validated HPLC method for the determination of B-complex vitamins in pharmaceutical formulations and biological fluids after solid phase extraction, J. Sep. Sci 27: 1181-1188.
  • Choi Y.H., Kim H.K., Hazekamp A., Erkelens C., Lefeber A.W.M. & Verpoorte R. (2004), Metabolomic Differentiation of Cannabis sativa Cultivars Using 1H-NMR and Principal Component Analysis, J. Nat. Prod. 67: 953-957.
  • Rhee I.K., Appels N., Hofte B., Karabatak B., Erkelens C., Stark L.M., Flippin L.A. & Verpoorte R. (2004), Isolation of the Acetylcholinesterase inhibitor ungeremine from Nerine bowdenii isolated by preparative HPLC coupled online to a flow assay system, Biological Pharmaceutical Bulletin 27: 1804-1809.
  • Frederich M., Choi Y.H., Angenot L., Harnischfeger G., Lefeber A.W.M., Erkelens C. & Verpoorte R. (2004), Metabolomic analysis of Strychnos nux-vomica, Strychnos icaja and Strychnos ignatii extracts by 1 H nuclear magnetic resonance spectrometry and multivariate analysis techniques, Phytochemistry 65: 1993-2001.
  • Rhee I.K., Appels N., Luijendijk T., Irth H. & Verpoorte R. (2003), Determining Acetylcholinesterase Inhibitory activity in Plant Extracts using a Fluorometric Flow Assay, Phytochemical Analysis 14: 145-149.
  • Mustafa N.K., Rhee I.K. & Verpoorte R. (2003), Rapid method for determination of galanthaminie in Amaryllidaceae plants using high performance liquid chromatography, J. Liq. Chrom. & Rel. Technol. 26: 3217-3224.
  • Kim H.K., Choi Y.H., Wen-Te Chang R. & Verpoorte R. (2003), Quantitative analysis of ephedrine analogues from Ephedra species using H-1-NMR, Chemical and pharmaceutical bulletin 51: 1382-1385.
  • Rhee I.K., Rijn R.M. van & Verpoorte R. (2003), Qualitative determination of false-positive effects in the acetylcholinesterase assays using thin layer chromatography, Phytochemical Analysis 14: 127-131.
  • Twyman R.M., Verpoorte R., Memlink J. & Christou P. (2003), Genetic modification of secondary metablism: Alkaloids. In: Thomas B. Murphy, Marray B. (Red.) Encyclopedia of Applied Plant Sciences. New York: Academic Press. 493-500.
  • Choi Y.H., Choi H.-K., Hazekamp A., Bermejo P., Schilder Y.D.C., Erkelens C. & Verpoorte R. (2003), Quantitative analysis of bilobalide and ginkgolides from Ginkgo biloba leaves and Ginkgo products using H-1-NMR, Chemical and pharmaceutical bulletin 51: 158-161.
  • El Hassan A., El-Sayed M., Hamed A.I., Rhee I.K., Ahmed A.A., Zeller K.P. & Verpoorte R. (2003), Bioactive constituents of Leptadenia arborea, Fitoterapia 74: 184-187.
  • Han Y.-S., Hofte B., Heijden R. van der & Verpoorte R. (2003), Analysis of anthraquinones in cell cultures of Cinchona "robusta" by HPLC with diode array and mass spectrometry detection, Phytochemical Analysis 14: 298-305.
  • Thongphasuk P., Suttisri R., Bavovada R. & Verpoorte R. (2003), Alkaloids and a pimarane diterpenoid from Strychnos vanprukii, Phytochemistry 64: 897-901.
  • Whitmer S., Canel C., Heijden R. van der & Verpoorte R. (2003), Long-term instability of alkaloid production by stably transformed cell lines of Catharanthus roseus, Plant Cell Tissue and Organ Culture 74: 73-80.
  • Han Y.-S., Hofte B., Heijden R. van der & Verpoorte R. (2003), Analysis of Anthraquinones in Cell Cultures of Cinchona ‘Robusta” by HPLC with Photodiode Array and Mass Spectrometry Detection, Phytochemical Analysis 14: 298-305.
  • Taesotikul T., Panthong A., Kanjanapothi D., Verpoorte R. & Scheffer J.J.C. (2003), Anti-inflammatory, antipyretic and antinociceptive activities of Tabernaemontana pandacaqui, Journal of Ethnopharmacology 84: 31-35.
  • Unver N., Kaya G.I., Werner C., Verpoorte R. & Gözler B. (2003), Galanthindole: a new indole alkaloid from Galanthus plicatus ssp. byzantinus, Planta Medica 69: 869-871.
  • Trevisan M.T.S., Viana Macedo F., Meent M. van de, Rhee I.K. & Verpoorte R. (2003), Selecão de plantas com atividade anticolinasterase para tratamento da doenca de Alzheimer, Quimica Nova 26: 301-304.
  • Han Y.-S., Sabbioni C., Heijden R. van der & Verpoorte R. (2003), High-performance liquid chromatography assay for 1-deoxy-D-xylulose 5-phosphate synthase activity using fluorescence detection, Journal of Chromatography A 986: 291-296.
  • Frederich M., Choi Y.H. & Verpoorte R. (2003), Quantitative analysis of strychnine and brucine in Strychnos nux-vomica using H-1-NMR, Planta Medica 69: 1169-1171.
  • Halim V.A., Verberne M.C. & Verpoorte R. (2003), Differential metabolic profiling by HPLC-PDA-MS of wild type and transgenic tobacco plants constitutively producing salicylic acid, J. Liq. Chrom. & Rel. Technol. 26: 369-383.
  • Rhee I.K., Appels N., Luijendijk T., Irth H. & Verpoorte R. (2003), Determining acetylcholinesterase inhibitory activity in plant extracts using a fluorimetric flow assay, Phytochemical Analysis 14: 145-149.
  • Budi Muljuno R.A., Scheffer J.J.C. & Verpoorte R. (2003), Effect of feeding salicyclic acid on 2,3-dihydroxybenzoic acid formation in cultured cells of Catharanthus roseus, Pharm. Biol. 41: 284-291.
  • Trevisan M.T.S., Scheffer J.J.C. & Verpoorte R. (2003), Peroxidase activity in hop plants after infestation by red spider mites, Crop protection 22: 423-424.
  • Han Y.-S., Roytrakul S., Verberne M.C., Heijden R. van der, Linthorst H.J.M. & Verpoorte R. (2003), Cloning of a cDNA encoding 1-deoxy-D-xylulose 5-phosphate synthase from Morinda citrifolia and analysis of its expression in relation to anthraquinone accumulation, Plant Science 164: 911-917.
  • Pelser P.B., Kruijer H.J.D. & Verpoorte R. (2002), What is the function of oil-containing rudimentery branches in the moss Canalohypopterygium tamariscinum (Hedw.) Kruijer (Hypopterygiaceae), New Zealand J. Bot. 40: 149-153.
  • Ingkaninan K., Irth H. & Verpoorte R. (2002), Screening of Amaryllidaceae for biological activities: Acetylcholineesterase inhibitors in Narcissus.. In: Hanks, G.R. (Red.) The genus Narcissus. London: Harwood Pulishers. 369-379.
  • Araujo P.S., Maraschin M., Passos Maraschin R. dos, Caro M.G.S. & Verpoorte R. (2002), Kinetics of the carbohydrate metabolism in Mandevilla velutina cell cultures by 1HNMR, Applied Magnetic Resonance 1: 102-109.
  • Nugroho L.H. & Verpoorte R. (2002), Secondary metabolism in tobacco, Plant Cell Tissue and Organ Culture 68: 105-125.
  • Nugroho L.H., Verberne M.C. & Verpoorte R. (2002), Activities of enzymes involved in the phenylpropanoid pathway in constitutive salicylic acid producing transgenic tobacco plants, Plant Physiology and Biochemistry 40: 755-760.
  • Budi Muljono R.A., Scheffer J.J.C., Talou J.R. & Verpoorte R. (2002), Biosynthesis of 2,3-dihydroxybenzoic acid in transgenic Catharanthus roseus cell cultures overpressing isochorismate synthase, Heterocycles 56: 341-352.
  • El-Sayed M. & Verpoorte R. (2002), Effect of phytohormones on growth and alkaloid accumulation by a Catharanthus roseus cell suspension culture fed with precursors of the alkaloid biosynthesis, Plant Cell Tissue and Organ Culture 68: 265-270.
  • Verpoorte R., Contin A. & Memelink J. (2002), Biotechnology for the production of plant secondary metabolites, Phytochemistry Reviews 1: 13-25.
  • Han Y.S., Heijden R. van der, Lefeber A.W.M., Erkelens C. & Verpoorte R. (2002), Biosynthesis of antrhraquinones in Cell Cultures of Cinchona Robusta proceeds via the Methylerythritol 4-Phosphate Pathway, Phytochemistry 59: 45-55.
  • Maraschin M., Sugui J.A., Wood K.V., Bonham C., Buchi D.F., Cantao M.P., Carobrez S.G., Araujo P.S., Peixoto M.L., Verpoorte R. & Fontana J.D. (2002), Somaclonal variation: a morphogenetic and biochemical approach in Mandevilla velutina cultured cells, Braz. J. Med. Biol. Res. 35: 633-643.
  • Kraemer K.H., Stival A.L., Ferreira A.G., Schenkel E.P. & Verpoorte R. (2002), Ilex paraguariensis cell suspension culture characterization and response against ethanol, Plant Cell Tissue and Organ Culture 68: 57-63.
  • Alam G., Wahyuono S., Ganjar I.G., Hakim L., Timmerman H. & Verpoorte R. (2002), Tracheospasmolytic activity of viteosin-A and vitexicarpin isolated from Vitex trifolia, Planta Medica 68: 1047-1049.
  • Lucumi E., Vera A., Hallard D., Heijden R. van der & Verpoorte R. (2002), Alkaloid Formation in Cell Suspension Cultures of Tabernaemontana elegans after Feeding of Tryptamine and Loganin or Secologanin, Plant Cell Tissue and Organ Culture 68: 293-299.
  • Nugroho L.H., Peltenburg-Looman A.M.G., Verberne M.C. & Verpoorte R. (2002), Is accumulation of sesquiterpenoid phytoalexins induced in tobacco plants constitutively producing salicylic acid?, Plant Science 162: 989-993.
  • Budi Muljono R.A., Scheffer J.J.C. & Verpoorte R. (2002), Isochorismate is an intermediate in 2,3-dihydroxybenzoic acid biosynthesis in Cathranthus roseus cell cultures, Plant Physiology and Biochemistry 40: 231-234.
  • Verpoorte R., Ingkaninan K., Memelink J. & Heijden R. van der (2002), New perspectives for plant secondary metabolite production. In: Rauter, A.P., Palma, F.B., Justino, J. Araujo, M.E.A., dos Santos, S.P. (Red.) Proceedings Phytochemical Society of Europe. Dordrecht: Kluwer Academic Publishers. 345-366.
  • Nugroho L.H., Peltenburg-Looman A.M.G., Vos H. de, Verberne M.C. & Verpoorte R. (2002), Nicotine and related alkaloids accumulation in constitutive salicylic acid producing tobacco plants, Plant Science 162: 575-581.
  • Han Y.-S., Heijden R. van der & Verpoorte R. (2002), Improved anthraquinone accumulation in cell cultures of Cinchona "robusta" by feeding of biosynthetic precursors and inhibitors, Biotechnology Letters 24: 705-710.
  • Hoopen H.J.G. ten, Vinke J.L., Moreno P.R.H., Verpoorte R. & Heijnen J.J. (2002), Influence of temperature on growth and ajmalicine production by Catharanthus roseus suspension cultures, Enzyme and Microbial Technology 30: 56-65.
  • Verberne M.C., Brouwer N., Delbianco F., Linthorst H.J.M., Bol J.F. & Verpoorte R. (2002), Method for the extraction of the volatile compound salicyclic acid from tobacco leaf material, Phytochemical Analysis 13: 45-50.
  • Dignum M., Kerler J. & Verpoorte R. (2002), Vanilla curing under laboratory conditions, Food Chemistry 79: 165-171.
  • Verpoorte R. & Memelink J. (2002), Engineering secondary metabolite production in plants, Current opinion in biotechnology 13: 181-187.
  • Whitmer S., Heijden R. van der & Verpoorte R. (2002), Genetic engineering of the plant cell factory for secondary metabolite production. Indole Alkaloid production in Catharanthus roseus as a model. In: Oksman-Caldentey, K.M., Barz, W.H. (Red.) Plant biotechnology and transgenic plants. New York: Marcel Dekker. 373-404.
  • Dignum M.J.W. & Verpoorte R. (2002), Glucosylation of exogenous vanillin by plant cell cultures, Plant Cell Tissue and Organ Culture 69: 177-182.
  • Whitmer S., Heijden R. van der & Verpoorte R. (2002), Effect of precursor feeding on alkaloid accumulation by a tryptophan decarboxylase overexpressing transgenic cell line T22 of Catharanthus roseus, Journal of Biotechnology 96: 193-203.
  • Luckiewicz M., Zarate R., Dembinska-Migas W., Migas P. & Verpoorte R. (2002), Production of pulchelin E in hairy roots, callus and suspension cultures of Rudbeckia hirta L., Plant Science 163: 91-100.
  • Whitmer S., Heijden R. van der & Verpoorte R. (2002), Effect of precursor feeding on alkaloid accumulation by a strictosidine synthase over-expessing transgenic cell line S1 of Catharanthus roseus, Plant Cell Tissue and Organ Culture 69: 85-93.
  • Heijden R. van der & Verpoorte R. (2002), Effects of alkaloid precursor feeding on a Camptotheca acuminata cell line, Plant Physiology and Biochemistry 40: 749-753.
  • Geerlings A., Redondo F.J., Memelink J., Contin A., Heijden R. van der & Verpoorte R. (1999), Screening method for cDNAs encoding putative enzymes converting loganin into secologanin by a transgenic yeast culture, Biotechnology Letters 13: 605-608.
  • Ouwerkerk P.B.F., Hallard D., Verpoorte R. & Memelink J. (1999), Identification of UV-B ligt responsive regions in the promoter of the tryptophan decarboxylase gene from Catharanthus roseus, Plant Molecular Biology 41: 491-503.
  • Ouwerkerk P.B.F., Hallard D., Verpoorte R. & Memelink J. (1999), Identification of UV-B light-responsive regions in the promoter of the tryptophan decarboxylase gene from Catharanthus roseus, Plant Molecular Biology 41: 491-503.
  • Verpoorte R., Heijden R. van der, Hoopen G. ten & Memelink J. (1999), Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals, Biotechnology Letters 21: 467-479.
  • Verpoorte R., Heijden R. van der, Hoopen G. ten & Memelink J. (1999), Novel approaches to improve plant secondary metabolite production. In: Fu T-J, Singh G., Curtis W.R. (Red.) Plant Cell and Tissue Culture for the Production of Food Ingredients. New York: Kluwer Academic/Plenum Publishers. 85-100.
  • Verpoorte R., Heijden R. van der, Memelink J. & Hoopen G. ten (1999), Metabolic engeering: A strategy to improve plant secondary metabolite production. In: Hostettmann K., Gupta M.P., Marston A. (Red.) Chemistry, biological and pharmacological properties of medicinal plants from the Americas. Amsterdam: Harwood Academic Publishers. 207-219.
  • Zárate R., Memelink J., Heijden R. van der & Verpoorte R. (1999), Genetic transformation via particle bombardment of Catharanthus roseus plants through adventitious organogenesis of buds, Biotechnology Letters 21: 997-1002.
  • Verpoorte R. (1998), Chemodiversity and the biological role of secondary metabolites, some thoughts for selecting plant material or drug develpment. In: Bohlin L., Bruhn J.G. (Red.) Bioassay Methods in Natural Product Research and Drug Development. Dordrecht, NL: Kluwer Academic Publishers. 11-24.
  • Hofte A.J.P., Hoeven R.A.M. van der, Fung S.Y. & Verpoorte R. (1998), Characterization of Hop Acids by liquid Chromatography with Negative Electrospray Iozination Mass Spectrometry, Journal American Society Brewing Chemists 56: 118-122.
  • Hallard D., Heijden R. van der, Contin A., Tomas Jiménéz E.M., Snoeijer W., Verpoorte R., Jensen S.R., Lopes Cardoso M.I., Pasquali G., Memelink J. & Hoge J.H.C. (1998), An assay for secologanin in plant tissues based on enzymatic conversion into strictosidine, Phytochemical Analysis 9: 162-167.
  • Contin A., Heijden R. van der, Lefeber A.W.M. & Verpoorte R. (1998), The iridoid glucoside secologanin is derived from the novel triose phosphate/pyruvate pathway in a Catharanthus roseus cell culture, FEBS Letters 434: 413-416.
  • Hofte A.J.P., Hoeven R.A.M. van der, Fung S.Y., Verpoorte R., Tjaden U.R. & Greef J. van der (1998), Characterization of hop acids by liquid chromatography with negative electrospray ionization mass spectrometry, Journal American Soc Brew Chem 56(3): 118-122.
  • Taesotikul T., Panthong A., Kanjanapothi D., Verpoorte R. & Scheffer J.J.C. (1998), Neuropharmacological activities of the crude alkaloidal fraction from stems of Tabernaemontana pandacaqui Poir, Ethnopharmacology 62: 229-234.
  • Zuurbier K.W.M., Fung S.Y., Scheffer J.J.C. & Verpoorte R. (1998), In-vitro prenylation of aromatic intermediates in the biosynthesis of bitter acids in Humulus lupulus, Phytochemistry 49: 2315-2322.
  • Heijden R. van der, Schulte A.E., Ramos-Valdivia A.C. & Verpoorte R. (1998), Characterization of some isoprenoid-biosynthesic enzymes from plant cell cultures. In: Kieslich K., Bont J.A.M. de, Beek C.P. van der, Tweel W.J.J. van den (Red.) Studies in Organic Chemistry, Vol 53, New Frontiers in screening for microbial biocatalysts. Amsterdam, NL: Elsevier. 177-185.
  • Theodoridis G., Laskaris G., Jong C.F. de, Hofte A.J.P. & Verpoorte R. (1998), Determination of paclitaxel and related diterpenoids in plant extracts by high-performance liquid chromatography with UV detection in high-performance liquid chromatography-mass spectrometry, Journal of Chromatography A 802: 297-305.
  • Höft M., Verpoorte R. & Beck E. (1998), Leaf alkaloid contents of Tabernaemontana pachysiphon as influenced by endogenous and environmental factors in the natural habitat, Planta Medica 64: 148-152.
  • Leech M.J., May K., Hallard D.A.C., Verpoorte R., Luca V. de & Christou P. (1998), Expression of two consecutive genes of a secondary metabolic pathway in transgenic tobacco: molecular diversity influences levels of expression and product accumulation, Plant Molecular Biology 38: 765-774.
  • Verpoorte R. (1998), Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development, Drug Discovery Today 3: 232-238.
  • Romeo J.T., Downum K.R. & Verpoorte R. (1998), Phytochemical signals and plant-microbe interactions. In: Romeo J.T., Downum K.R., Verpoorte R. (Red.) Recent Advances in Phytochemistry: Plenum Press.
  • Ramos-Valdivia A.C., Heijden R. van der & Verpoorte R. (1998), Isopentenyl diphosphate isomerase and prenyltransferase activities in rubiaceous and apocynaceous cultures, Phytochemistry 48: 961-969.
  • Contin A., Heijden R. van der, Hoopen G. ten & Verpoorte R. (1998), The inoculum size triggers tryptamine or secologanin biosynthesis in a Catharanthus roseus cell culture, Plant Science 139: 205-211.
  • Verpoorte R., Heijden R. van der & Memelink J. (1998), Plant biotechnology and the production of alkaloids: prospects of metabolic engineering. In: Cordell G.A. (Red.) The Alkaloids. San Diego, USA: Academic Press. 453-508.
  • Zuurbier K.W.M., Leser J., Berger T., Hofte A.J.P., Schröder G., Verpoorte R. & Schröder J. (1998), 4-Hydoxy-2-pyrone formation by chalcone and stilbene synthase with nonphysiological substrates, Phytochemistry 49(7): 1945-1951.
  • Canel C., Lopes Cardoso M.I., Whitmer S., Fits L. van der, Pasquali G., Heijden R. van der, Hoge J.H.C. & Verpoorte R. (1998), Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus, Planta 205: 414-419.
  • Rech S.B., Batista C.V.F., Schripsema J., Verpoorte R. & Henriques A.T. (1998), Cell cultures of Rauvolfia sellowii: growth and alkaloid production, Plant Cell Tissue and Organ Culture 54: 61-63.
  • Verpoorte R., Heijden R. van der, Hoopen G. ten & Memelink J. (1998), Metabolic engineering to improve plant secondary metabolite production, Plant Tissue Culture and Biotechnology 4: 3-20.
  • Budi Muljono R.A., Looman A.M.G., Verpoorte R. & Scheffer J.J.C. (1998), Assay of salicylic acid and related compounds in plant cell cultures by capillary GC, Phytochemical Analysis 9: 35-38.
  • Carrier D.J., Beek T.A. van, Heijden R. van der & Verpoorte R. (1998), Distribution of ginkgolides and terpenoid biosynthetic activity in Ginkgo biloba, Phytochemistry 48: 89-92.
  • Verberne M.C., Budi Muljono R.A. & Verpoorte R. (1998), Salicylic acid biosynthesis. In: Biochemistry and Molecular Biology of Plant Hormones. New Comprehensive Biochemistry. Amsterdam, NL: Elsevier.
  • Kraemer K.H., Schenkel E.P. & Verpoorte R. (1998), Biotransformation of alcohol in Ilex paraguariensis cell suspension cultures: triterpenes and carbohydrates, Plant Cell Reports.
  • Taesotikul T., Panthong A., Kanjanapothi D., Verpoorte R. & Scheffer J.J.C. (1998), Cardiovascular activity of the crude alkaloidal fraction from Tabernaemontana pandacaqui in the rat, Journal of Ethnopharmacology 59: 131-137.
  • Heijden R. van der & Verpoorte R. (1998), Metabolic engineering of plant secondary metabolism. In: In vitro plant cell engineering: Le Biopole Vegetal/IAPTC. 19-23.
  • Verpoorte R. (1998), Metabolic engineering as a strategy to improve the production of secondary metabolite production in plants or plant cell cultures, Acta Horticulture.
  • Luijendijk T.J.C., Stevens L.H. & Verpoorte R. (1998), Purification and characterisation of strictosidine ß-D-glucosidase from Catharanthus roseus cell suspension cultures, Plant Physiology and Biochemistry (Paris) 36: 419-425.
  • Gournelis D.C., Laskaris G. & Verpoorte R. (1998), Cyclopeptide alkaloids. In: Progress in the Chemistry of Organic Natural Products.. Wien, Austria: Springer-Verlag. 1-179.
  • Canel C., Lopes Cardoso M.I., Whitmer S., Fits L. van der, Pasquali G., Heijden R. van der, Hoge J.H.C. & Verpoorte R. (1998), Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus, Planta 205: 414-419.
  • Zuurbier K.W.M., Fung S.Y., Scheffer J.J.C. & Verpoorte R. (1998), In vitro prenylation of aromatic intermediates in the biosynthesis of bitter acids in humulus lupulus, Phytochemistry 49: 2315-2322.
  • Hallard D., Heijden R. van der, Contin A., Tomas Jimenez E.M., Snoeijer W., Verpoorte R., Jensen S.R., Lopes Cardoso M.I., Pasquali G., Memelink J. & Hoge J.H.C. (1998), An assay for secologanin in plant tissues based on enzymatic conversion into strictosidine, Phytochemical Analysis 9: 162-167.
  • Contin A., Heijden R. van der & Verpoorte R. (1998), Localization of secologanin in Catharanthus roseus cells, Acta Botanica Gallica.
  • Ingkaninan K., Hermans-Lokkerbol A.C.J. & Verpoorte R. (1998), Comparison of some centrifugal partition chromatography systems for a general separation of plant extracts, Journal of Liquid Chromatography and Related Technologies.
  • Theodoridis G., Jong C.F. de, Laskaris G. & Verpoorte R. (1998), Application of SPE for the HPLC analysis of taxanes from Taxus cell cultures, Chromatographia 47: 25-34.
  • Verpoorte R. (1998), Antimicrobial activity of alkaloids. In: Roberts M.F., Wink M. (Red.) Alkaloids: biochemistry, ecology and medicinal applications.. New York: Plenum Publishing Corporation. 397-433.
  • Contin A., Heijden R. van der & Verpoorte R. (1998), The effects of phenobarbital and ketoconazole on alkaloid biosynthesis in Catharanthus roseus cell suspension cultures, Plant Physiology and Biochemistry (Paris).
  • Akhtar M. T., Mushtaq M. Y., Verpoorte R., Richardson M. K. & Choi Y. H.. (), Metabolic effects of cannabinoids in zebrafish (Danio rerio) embryos determined by 1H NMR metabolomics., Metabolomics .
Populariserend
  • Heijden R. van der, Schulte A.E., Contin A. & Verpoorte R. (1998), Alternatieve biosynthese terpenoiden ontdekt. Chemisch Weekblad: 90-92.
Overig
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  • Pan Q., Mustafa N.R., Tang K., Choi Y.H. & Verpoorte R. (2015), Terpenoid indole alkaloids biosynthesis and its regulation in Catharanthus roseus. Phytochemistry Reviews. [overig]
  • Akhtar M.T., Mushtaq M.Y., Verpoorte R., Richardson M.K. & Choi Y.H. (2015), Metabolic effects of cannabinoids in zebrafisch (Danio Rerio) embryos determined by 1HNMR metabolomics. Metabolomics. [overig]
  • Spronsen J. van, Witkamp G.-J., Hollman F., Choi Y.H. & Verpoorte R. (2011), Process for extracting materials from biological material. ( octrooi nr. PCT/NL2011/050407). [octrooi]
  • Verpoorte R. (12 september 2011), Geneesmiddelen en planten. (Lezing).
  • Verpoorte R., Choi Y.H., Witkamp G.-J., Spronsen J. van & Hollmann F. (2010), Natural ionic liquids and deep eutectic solvents for industrial, pharmaceutical, cosmetic and consumers applications ( octrooi nr. 2004835). [octrooi]
  • Lubbe A., Zuidgeest J., Gude H. & Verpoorte R. (2010), Method for the production of glycosides from bulbs and use of the glycosides thus produced ( octrooi nr. N2005573). [octrooi]
  • Verpoorte R. (Red.) (2010), Comprehensive Natural Products II Chemistry and Biology. Oxford: Elsevier.
  • Verpoorte R. (1998), Production of hop bitter acids (Lezing). Linz, Austria.
  • Verpoorte R. (1998), Plant cell biotechnology for the production of secondary metabolites (Lezing). Caxias, Brazil.
  • Verpoorte R. (1998), Metabolic engineering to increase plant secondary metabolite production (Lezing). Buenos Aires, Argentina.
  • Verpoorte R. (1998), Plant cell biotechnology for the production of secondary metabolites (Lezing). Yogyakarta, Indonesia.
  • Verpoorte R. (1998), Metabolic engineering: a novel approach to the improvement of secondary metabolite production in plants or plant cell cultures (Lezing). Talca, Chile.
  • Verpoorte R. (1998), Biosynthesis of hop bitter acids (Lezing). Chiang May, Thailand.
  • Verpoorte R. (1998), Biosynthesis of hop bitter acids (Lezing). Chiba, Japan.
  • Verpoorte R. (1998), Biosynthesis of bitter acids in hops (Lezing). Yakima, USA.
  • Verpoorte R. (1998), Biosynthesis of terpenoid indole alkaloids: target for metabolic engineering (Lezing). Istanbul, Turkey.
  • Verpoorte R. (1998), Engineering plant secondary metabolism: problems and prospects (Lezing). Jealott's Hill, UK.
  • Verpoorte R. (1998), Biodiversity, source of genes for genetic engineering plant secondary metabolism (Lezing). San José, Costa Rica.
  • Verpoorte R. (1998), Engineering plant secondary metabolism: prospects and problems (Lezing). Bogor, Indonesia.
  • Verpoorte R. (1998), Metabolic engineering, improving production of plant secondary metabolism (Lezing). Pereira, Columbia.

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